MODERN APPROACH TOWARDS IMMUNOMODULATION THERAPY

Local immunomodulation for cancer therapy

In murine models of cancer, we have achieved efficient systemic activation of tumor-specific T cells by the local administration of a CTLA4-blocking antibody at low doses. Using a slow-release formulation, we could drastically lower the serum levels of the antibody, hence decreasing adverse effects and the risk of autoimmune reactions, without losing systemic efficacy.

Evolvable Production Systems: Approach towards Modern Production Systems

To face current socio-economic adverse conditions enterprises must increase their efficiency and evolve to the requirements of customization and sustainability. Modern production systems need to deal with instability of markets and resource scarcity regarding an economical, ecological and social concern. The Evolvable Production Systems (EPS) has aimed at developing such technological solutions...

Immunomodulation Therapy for Severe Aplastic Anemia

Towards Modern Literate Programming

Literate programming was invented by Donald Knuth as a technique for improved documentation of program understanding. It involves writing code and documentation in a single source document, ordered for comprehension by humans rather than computers. Despite its ability to produce software of higher quality and maintainability, the technique is not widely used. In this report, we present a compre...

Towards a Modern Communications API

We contend that a new networking API could better serve the needs of dataand service-oriented applications, and could more easily map to heterogeneous environments, than the pervasive Sockets API does. In this paper, we present an initial design of a networking API based on the publish/subscribe paradigm, along with an exploration of its security implications, examples to demonstrate several co...